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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804144Generated: October 27, 2026

2-Oxazolidinone → 3-{4-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]-3-fluorophenyl}oxazolidin-2-one

https://huagongshe.com/reaction/1804144

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(4-Bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanoneHCID 58484705—
Product3-{4-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]-3-fluorophenyl}oxazolidin-2-oneHCID 4618994648.2%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (783 mg) described in Preparation Example 4 and oxazolidin-2-one (174 mg), the title compound (383 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-36374235ba704587a14329e0bf8fc3d4
Source noteuspto-grants-2013_01