Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804170Generated: October 31, 2026

2-Oxazolidinone → 3-{5-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-one

https://huagongshe.com/reaction/1804170

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
ReactantHCID 58484755HCID 58484755—
Product3-{5-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-oneHCID 6738141362.2%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (6-bromopyridin-3-yl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (749 mg) described in Preparation Example 20 and oxazolidin-2-one (174 mg), the title compound (473 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-f2f048de7f544d33bf4c905382a90c5d
Source noteuspto-grants-2013_01