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HRID1804181

反应详情

EQUATION

反应方程式

HRID 1804181 的结构方程式

REACTANTS

反应物

2
结构：CC[C@@H]1COC(=O)N1
HCID641503

(4R)-4-ethyl-1,3-oxazolidin-2-one

C5H9NO2

结构：Cc1ccc(OC2CCN(C(=O)c3ccc(Br)nc3)CC2)cc1
HCID58484591

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCC(Oc3ccc(C)cc3)CC2)cn1
HCID46190176

未命名化合物

收率 20%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 40 and using (6-bromopyridin-3-yl)(4-p-tolyloxypiperidin-1-yl)methanone (1.2 g) described in Preparation Example 28 and (R)-4-ethyloxazolidin-2-one (525 mg) described in Preparation Example 26, the title compound (262 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 40
  2. customdescribed in Preparation Example 26