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HRID1804193

反应详情

EQUATION

反应方程式

HRID 1804193 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484719

未命名化合物

结构：Cc1cnc(N2CCNCC2)c(C)c1.Cl
HCID67381379

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3)CC2)c(C)c1
HCID67380797

未命名化合物

收率 72.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 49 and using (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (442 mg) described in Preparation Example 37 and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (455 mg) described in Preparation Example 64, the title compound (571 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 49
  2. customdescribed in Preparation Example 64