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HRID1804197

反应详情

EQUATION

反应方程式

HRID 1804197 的结构方程式

REACTANTS

反应物

2
结构：CCC[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484846

未命名化合物

结构：Cc1cnc(N2CCNCC2)c(C)c1.Cl
HCID67381379

未命名化合物

PRODUCTS

生成物

1
结构：CCC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1
HCID67380815

未命名化合物

收率 28.3%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 49 and using (R)-4-(2-oxo-4-propyloxazolidin-3-yl)benzoic acid (498 mg) described in Preparation Example 79 and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (455 mg) described in Preparation Example 64, the title compound (239 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 49
  2. customdescribed in Preparation Example 64