HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-4-Methyloxazolidin-2-one → HCID 67381178, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-4-Methyloxazolidin-2-one | HCID 2734858 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Product | HCID 67381178 | HCID 67381178 | 22.9% |
Reaction Steps
By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (893 mg) described in Preparation Example 65 and (R)-4-methyloxazolidin-2-one (231 mg) described in Preparation Example 25, the title compound (215 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-081f961c5e634b26938b06e13218a28b |
| Source note | uspto-grants-2013_01 |