HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68585773, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (+/-)-cis 1-Hydroxy-6-methoxy-3,3,14-trimethyl-7-oxo-2,3,7,14-tetrahydro-1H-benzo[b]chromeno[6,5-g][1,8]naphthyridin-2-yl butyrate | HCID 131728189 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68585773 | HCID 68585773 | — |
Reaction Steps
Add 4 drops of a 10% solution of HCl to a solution of 0.29 mmol of the compound of Example 13 in 6 ml of dichloromethane. The reaction mixture is stirred for 3 days at ambient temperature and then dried and concentrated under reduced pressure. Chromatography of the residue on silica gel (dichloromethane/methanol gradient) allows the expected product to be isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741325B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-c58c4d2699ab4fa7bc11164dc9ec05bd |
| Source note | uspto-grants-2010_06 |