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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804204Generated: November 2, 2026

4-(5-Methyl-2-oxooxazolidin-3-yl)benzoic acid → 3-{4-[4-(3,5-Dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-5-methyloxazolidin-2-one

https://huagongshe.com/reaction/1804204

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Methyl-2-oxooxazolidin-3-yl)benzoic acidHCID 58484866—
Reactant1-(3,5-Dimethylpyridin-2-yl)piperazine hydrochlorideHCID 67381379—
Product3-{4-[4-(3,5-Dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-5-methyloxazolidin-2-oneHCID 6738100534.5%

Reaction Steps

By reaction and treatment in the same manner as in Example 49 and using 4-(5-methyl-2-oxooxazolidin-3-yl)benzoic acid (442 mg) described in Preparation Example 40 and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (455 mg) described in Preparation Example 64, the title compound (272 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-b0708a614c13462da8c6cbcc99f4ade1
Source noteuspto-grants-2013_01