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HRID1804208

反应详情

EQUATION

反应方程式

HRID 1804208 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484719

未命名化合物

结构：Cc1cc(C2CC2)cnc1N1CCNCC1.Cl
HCID67381091

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C(=O)OC[C@H]3C)cc2)CC1
HCID67380979

未命名化合物

收率 70.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 49 and using (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (221 mg) described in Preparation Example 37 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochloride (254 mg) described in Preparation Example 49, the title compound (296 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 49
  2. customdescribed in Preparation Example 49