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HRID1804215

反应详情

EQUATION

反应方程式

HRID 1804215 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484719

未命名化合物

结构：Cc1cc(C)c(N2CCNCC2)nc1C.Cl
HCID67381052

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C)c(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3)CC2)nc1C.Cl
HCID67381351

未命名化合物

收率 79.5%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 87 and using (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (422 mg) described in Preparation Example 37 and 1-(3,5,6-trimethylpyridin-2-yl)piperazine hydrochloride (483 mg) described in Preparation Example 52, the title compound (675 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 87
  2. customdescribed in Preparation Example 52