HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4S)-4-(Benzoyloxymethyl)oxazolidine-2-one → HCID 67380964, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4S)-4-(Benzoyloxymethyl)oxazolidine-2-one | HCID 16213752 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Product | HCID 67380964 | HCID 67380964 | 21.2% |
Reaction Steps
By reaction and treatment in the same manner as in Example 19 and using (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (1.2 g) described in Preparation Example 65 and benzoic acid (R)-2-oxooxazolidin-4-ylmethyl ester (849 mg), the title compound (278 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-6d187ab49d28475bbeaaad34f1dfa18f |
| Source note | uspto-grants-2013_01 |