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HRID1804226

反应详情

EQUATION

反应方程式

HRID 1804226 的结构方程式

REACTANTS

反应物

2
结构：CC(C)[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484694

未命名化合物

结构：Cl.c1nc(N2CCNCC2)c(C2CC2)cc1C1CC1
HCID67381094

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C4CC4)cc3C3CC3)CC2)cc1.Cl
HCID67381205

未命名化合物

收率 45.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 87 and using (R)-4-(4-isopropyl-2-oxooxazolidin-3-yl)benzoic acid (499 mg) described in Preparation Example 18 and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine hydrochloride (560 mg) described in Preparation Example 50, the title compound (469 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 87
  2. customdescribed in Preparation Example 50