huagongshe.com
HRID1804246

反应详情

EQUATION

反应方程式

HRID 1804246 的结构方程式

REACTANTS

反应物

2
结构：C[C@H]1CNC(=O)O1
HCID21794663

未命名化合物

结构：O=C(c1ccc(I)cc1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1
HCID58484688

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H]1CN(c2ccc(C(=O)N3CCN(c4ncc(C5CC5)cc4C4CC4)CC3)cc2)C(=O)O1
HCID67380974

未命名化合物

收率 76.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using [4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (473 mg) described in Preparation Example 95 and (S)-5-methyloxazolidin-2-one (121 mg) described in Preparation Example 42, the title compound (343 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149
  2. customdescribed in Preparation Example 42