HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Oxazolidinone → 3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Oxazolidinone | HCID 73949 | — |
| Edukt | [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484841 | — |
| Produkt | 3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one | HCID 67381168 | 80,5% |
Reaktionsschritte
By reaction and treatment in the same manner as in Example 149 and using [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (447 mg) described in Preparation Example 97 and oxazolidin-2-one (104 mg)), the title compound (327 mg) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-f1c1446c0f9f47e0bace5d4338bb1ae0 |
| Quellennotiz | uspto-grants-2013_01 |