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HRID1804250

反应详情

EQUATION

反应方程式

HRID 1804250 的结构方程式

REACTANTS

反应物

2
结构：C[C@H]1CNC(=O)O1
HCID21794663

未命名化合物

结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(I)cc2)CC1
HCID58484841

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C[C@H](C)OC3=O)cc2)CC1
HCID67380879

未命名化合物

收率 81.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (447 mg) described in Preparation Example 97 and (S)-5-methyloxazolidin-2-one (121 mg) described in Preparation Example 42, the title compound (344 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149
  2. customdescribed in Preparation Example 42