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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804265Generated: October 26, 2026

2-Oxazolidinone, 5,5-dimethyl- → 3-{5-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}-5,5-dimethyloxazolidin-2-one

https://huagongshe.com/reaction/1804265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxazolidinone, 5,5-dimethyl-HCID 136892—
Reactant(6-Bromopyridin-3-yl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484858—
Product3-{5-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}-5,5-dimethyloxazolidin-2-oneHCID 5848466869%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (6-bromopyridin-3-yl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (525 mg) described in Preparation Example 106 and 5,5-dimethyloxazolidin-2-one (242 mg) described in Preparation Example 43, the title compound (393 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-2a9cc9a71e3540549a4a2f1a53086549
Source noteuspto-grants-2013_01