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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804267Generated: October 25, 2026

2-Oxazolidinone → 3-{5-[4-(3,5-Dicyclopropylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-one

https://huagongshe.com/reaction/1804267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(6-Bromopyridin-3-yl)[4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484777—
Product3-{5-[4-(3,5-Dicyclopropylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-oneHCID 5848462026.5%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (6-bromopyridin-3-yl)[4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl]methanone (641 mg) described in Preparation Example 112 and oxazolidin-2-one (200 mg), the title compound (172 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-32aadd23bcf44fb4b4286837e0842e1a
Source noteuspto-grants-2013_01