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HRID1804270

反应详情

EQUATION

反应方程式

HRID 1804270 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)CNC(=O)O1
HCID136892

2-Oxazolidinone, 5,5-dimethyl-

C5H9NO2

结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1
HCID58484842

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CC(C)(C)OC3=O)cc2F)CC1
HCID58484685

未命名化合物

收率 22.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (480 mg) described in Preparation Example 86 and 5,5-dimethyloxazolidin-2-one (196 mg) described in Preparation Example 43, the title compound (119 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 1
  2. customdescribed in Preparation Example 43