HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58484543, compound → HCID 58484580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58484543 | HCID 58484543 | — |
| Reactant | [4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484716 | — |
| Product | HCID 58484580 | HCID 58484580 | 71.4% |
Reaction Steps
By reaction and treatment in the same manner as in Example 1 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (247 mg) described in Preparation Example 118 and (R)-4-methoxymethyloxazolidin-2-one (65.6 mg) described in Preparation Example 38, the title compound (194.2 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-29e5846f7040408eb6c6d8cdd3779094 |
| Source note | uspto-grants-2013_01 |