(4R)-4-Propyl-2-oxazolidinone → (R)-3-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-3-(1,1-dioxoisothiazolidin-2-yl)phenyl}-4-propyloxazolidin-2-one

Participants

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (247 mg) described in Preparation Example 118 and (R)-4-propyloxazolidin-2-one (64.58 mg) described in Preparation Example 29, the title compound (188.8 mg) was obtained.

Provenance & Evidence