huagongshe.com
HRID1804290

反应详情

EQUATION

反应方程式

HRID 1804290 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3N3CCN(C)C3=O)CC2)c(C)c1
HCID58484802

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3N3CCN(C)C3=O)CC2)c(C)c1
HCID58484570

未命名化合物

收率 39%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 201 and using 1-{5-chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-3-methylimidazolidin-2-one (184 mg) described in Preparation Example 127 and (R)-4-methyloxazolidin-2-one (47.8 mg) described in Preparation Example 25, the title compound (82.6 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 201
  2. customdescribed in Preparation Example 25