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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804293Generated: October 30, 2026

2-Oxazolidinone → 3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methanesulfonylaminophenyl}oxazolidin-2-one

https://huagongshe.com/reaction/1804293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
ReactantN-{5-bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}methanesulfonamideHCID 58484826—
Product3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methanesulfonylaminophenyl}oxazolidin-2-oneHCID 5848468432.1%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using N-{5-bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}methanesulfonamide (247 mg) described in Preparation Example 124 and oxazolidin-2-one (43.5 mg), the title compound (80.1 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-d0681a325b744163992e4a4c28732b30
Source noteuspto-grants-2013_01