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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804296Generated: October 30, 2026

2-Oxazolidinone → 3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methylphenyl}oxazolidin-2-one

https://huagongshe.com/reaction/1804296

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(4-Bromo-2-methylphenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484636—
Product3-{4-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methylphenyl}oxazolidin-2-oneHCID 5848453488.9%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-methylphenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (347 mg) described in Preparation Example 130 and oxazolidin-2-one (109 mg), the title compound (313 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-eebf8755f5d44e059713f51af25d2e39
Source noteuspto-grants-2013_01