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HRID1804301

反应详情

EQUATION

反应方程式

HRID 1804301 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：CCc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C)c1
HCID58484652

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)nc3)CC2)c(C)c1
HCID58484671

未命名化合物

收率 61.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 1 and using (6-bromopyridin-3-yl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (1.37 g) described in Preparation Example 115 and (R)-4-methyloxazolidin-2-one (0.53 g) described in Preparation Example 25, the title compound (892 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 1
  2. customdescribed in Preparation Example 25