(R)-4-Methyloxazolidin-2-one → (R)-3-{5-[4-(5-cyano-3-methylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}-4-methyloxazolidin-2-one

Participants

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using 6-[4-(6-bromopyridine-3-carbonyl)piperazin-1-yl]-5-methylnicotinonitrile (200 mg) described in Preparation Example 131 and (R)-4-methyloxazolidin-2-one (79 mg) described in Preparation Example 25, the title compound (170 mg) was obtained.

Provenance & Evidence