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HRID1804307

反应详情

EQUATION

反应方程式

HRID 1804307 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：Cc1cc(Br)ccc1C(=O)N1CCN(c2ncc(C#N)cc2C)CC1
HCID58484676

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(N2C(=O)OC[C@H]2C)ccc1C(=O)N1CCN(c2ncc(C#N)cc2C)CC1
HCID58484809

未命名化合物

收率 65.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 1 and using 6-[4-(4-bromo-2-methylbenzoyl)piperazin-1-yl]-5-methylnicotinonitrile (210 mg) described in Preparation Example 133 and (R)-4-methyloxazolidin-2-one (80 mg) described in Preparation Example 25, the title compound (145 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 1
  2. customdescribed in Preparation Example 25