Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804320Generated: October 31, 2026

2-Oxazolidinone → 3-{5-[4-(2,4,5-Trimethylphenyl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-one

https://huagongshe.com/reaction/1804320

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(6-Bromopyridin-3-yl)[4-(2,4,5-trimethylphenyl)piperazin-1-yl]methanoneHCID 58484642—
Product3-{5-[4-(2,4,5-Trimethylphenyl)piperazine-1-carbonyl]pyridin-2-yl}oxazolidin-2-oneHCID 5848449979%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (6-bromopyridin-3-yl)[4-(2,4,5-trimethylphenyl)piperazin-1-yl]methanone (430 mg) described in Preparation Example 143 and oxazolidin-2-one (128 mg), the title compound (345 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-4748fd7bdaca4b0fa7e2203dff79b0cd
Source noteuspto-grants-2013_01