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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804328Generated: November 1, 2026

2-Oxazolidinone → 3-{5-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methylpyridin-2-yl}-oxazolidin-2-one

https://huagongshe.com/reaction/1804328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](6-fluoro-5-methylpyridin-3-yl)methanoneHCID 58484721—
Product3-{5-[4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-methylpyridin-2-yl}-oxazolidin-2-oneHCID 5848459433.8%

Reaction Steps

By reaction and treatment in the same manner as in Example 240 and using [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](6-fluoro-5-methylpyridin-3-yl)methanone (500 mg) described in Preparation Example 147 and oxazolidin-2-one (246 mg), the title compound (201 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-c92297d886e5473183eab899bd4b13fe
Source noteuspto-grants-2013_01