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HRID1804330

反应详情

EQUATION

反应方程式

HRID 1804330 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：CCc1cnc(N2CCN(C(=O)c3cnc(F)c(C)c3)CC2)c(C)c1
HCID58484760

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3cnc(N4C(=O)OC[C@H]4C)c(C)c3)CC2)c(C)c1
HCID58484837

未命名化合物

收率 31.8%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 240 and using [4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl](6-fluoro-5-methylpyridin-3-yl)methanone (440 mg) described in Preparation Example 149 and (R)-4-methyloxazolidin-2-one (261 mg) described in Preparation Example 25, the title compound (173 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 240
  2. customdescribed in Preparation Example 25