HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Oxazol-2(5H)-one → 3-{4-[4-(3,5,6-Trimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Oxazol-2(5H)-one | HCID 14405094 | — |
| Reactant | (4-Iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484793 | — |
| Product | 3-{4-[4-(3,5,6-Trimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one | HCID 58484735 | 29.9% |
Reaction Steps
By reaction and treatment in the same manner as in Example 149 and using (4-iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (435 mg) described in Preparation Example 176 and oxazolin-2-one (104 mg), the title compound (118 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-04de3a60a56a4940a2412f67f709b96c |
| Source note | uspto-grants-2013_01 |