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HRID1804341

反应详情

EQUATION

反应方程式

HRID 1804341 的结构方程式

REACTANTS

反应物

2
结构：CC[C@@H]1COC(=O)N1
HCID641503

(4R)-4-ethyl-1,3-oxazolidin-2-one

C5H9NO2

结构：Cc1cc(C)c(N2CCN(C(=O)c3ccc(I)cc3)CC2)nc1C
HCID58484793

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3nc(C)c(C)cc3C)CC2)cc1
HCID58484807

未命名化合物

收率 77.2%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using (4-iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (435 mg) described in Preparation Example 176 and (R)-4-ethyloxazolidin-2-one (138 mg) described in Preparation Example 26, the title compound (326 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149
  2. customdescribed in Preparation Example 26