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HRID1804360

反应详情

EQUATION

反应方程式

HRID 1804360 的结构方程式

REACTANTS

反应物

2
结构：C[C@H]1CNC(=O)O1
HCID21794663

未命名化合物

结构：CCc1cnc(N2CCN(C(=O)c3ccc(I)cc3)CC2)c(C)c1
HCID58484605

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3ccc(N4C[C@H](C)OC4=O)cc3)CC2)c(C)c1
HCID58484541

未命名化合物

收率 80.8%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using [4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (435 mg) described in Preparation Example 177 and (S)-5-methyloxazolidin-2-one (121 mg) described in Preparation Example 42, the title compound (330 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149
  2. customdescribed in Preparation Example 42