HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4S)-4-(Benzoyloxymethyl)oxazolidine-2-one → HCID 58484649, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4S)-4-(Benzoyloxymethyl)oxazolidine-2-one | HCID 16213752 | — |
| Reactant | [4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484716 | — |
| Product | HCID 58484649 | HCID 58484649 | 66.2% |
Reaction Steps
By reaction and treatment in the same manner as in Preparation Example 91 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (986 mg) described in Preparation Example 118 and benzoic acid (R)-2-oxooxazolidin-4-ylmethyl ester (487 mg), the title compound (838 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-e46d214808ff45cbbad3fc0705335fa3 |
| Source note | uspto-grants-2013_01 |