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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804367Generated: October 26, 2026

5,5-Dimethyloxazolin-2-one → HCID 58484607, compound

https://huagongshe.com/reaction/1804367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,5-Dimethyloxazolin-2-oneHCID 21464782—
Reactant[4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484554—
ProductHCID 58484607HCID 5848460750.6%

Reaction Steps

By reaction and treatment in the same manner as in Example 110 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (779 mg) described in Preparation Example 179 and 5,5-dimethyloxazolin-2-one (207 mg) described in Preparation Example 43, the title compound (420 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-497d34dde56a4383abf4782487bdcd10
Source noteuspto-grants-2013_01