HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-4-Methyloxazolidin-2-one → HCID 58484717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-4-Methyloxazolidin-2-one | HCID 2734858 | — |
| Reactant | [4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484554 | — |
| Product | HCID 58484717 | HCID 58484717 | 84.4% |
Reaction Steps
By reaction and treatment in the same manner as in Example 149 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (519 mg) described in Preparation Example 179 and (R)-4-methyloxazolidin-2-one (121 mg) described in Preparation Example 25, the title compound (455 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-5601a95d226242399fff5ee390ad282a |
| Source note | uspto-grants-2013_01 |