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HRID1804372

反应详情

EQUATION

反应方程式

HRID 1804372 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：CCc1cnc(N2CCN(C(=O)c3ccc(Br)cc3N3CCCS3(=O)=O)CC2)c(C)c1
HCID58484567

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3N3CCCS3(=O)=O)CC2)c(C)c1
HCID58484803

未命名化合物

收率 89.9%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (507 mg) described in Preparation Example 180 and (R)-4-methyloxazolidin-2-one (121 mg) described in Preparation Example 25, the title compound (474 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149
  2. customdescribed in Preparation Example 25