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HRID1804373

反应详情

EQUATION

反应方程式

HRID 1804373 的结构方程式

REACTANTS

反应物

2
结构：O=C1N=CCO1
HCID14405094

1,3-Oxazol-2(5H)-one

C3H3NO2

结构：CCc1cnc(N2CCN(C(=O)c3ccc(Br)cc3N3CCCS3(=O)=O)CC2)c(C)c1
HCID58484567

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cnc(N2CCN(C(=O)c3ccc(N4CCOC4=O)cc3N3CCCS3(=O)=O)CC2)c(C)c1
HCID58484699

未命名化合物

收率 81.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 149 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (507 mg) described in Preparation Example 180 and oxazolin-2-one (104 mg), the title compound (419 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 149