HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-methyloxazolidin-2-one → HCID 58484828, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-methyloxazolidin-2-one | HCID 21794663 | — |
| Reactant | [4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484567 | — |
| Product | HCID 58484828 | HCID 58484828 | 82.9% |
Reaction Steps
By reaction and treatment in the same manner as in Example 149 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (507 mg) described in Preparation Example 180 and (S)-5-methyloxazolidin-2-one (121 mg) described in Preparation Example 42, the title compound (437 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-edd3262300814be793ccef20b5f4fbe9 |
| Source note | uspto-grants-2013_01 |