HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4R)-4-ethyl-1,3-oxazolidin-2-one → HCID 58484670, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4R)-4-ethyl-1,3-oxazolidin-2-one | HCID 641503 | — |
| Reactant | [4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484567 | — |
| Product | HCID 58484670 | HCID 58484670 | 84.8% |
Reaction Steps
By reaction and treatment in the same manner as in Example 149 and using [4-bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (507 mg) described in Preparation Example 180 and (R)-4-ethyloxazolidin-2-one (138 mg) described in Preparation Example 26, the title compound (459 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-236ac2f954d0431a8ffd8403d452a87a |
| Source note | uspto-grants-2013_01 |