6-[4-(2-aminoethoxy)-3-methyl-phenyl]-3(2H)-pyridazinone → 6-[4-[2-[3-(4-(2-Methoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-methyl-phenyl]-3-(2H)-pyridazinone

HRID 180453Notes

Reaction equation

HRID 180453 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][c:7]1[cH:8][cH:9][c:10]([O:11][CH2:12][CH:13]2[CH2:14][O:15]2)[cH:16][cH:17]1.[NH2:18][CH2:19][CH2:20][O:21][c:22]1[c:23]([CH3:35])[cH:24][c:25](-[c:28]2[cH:29][cH:30][c:31](=[O:34])[nH:32][n:33]2)[cH:26][cH:27]1>>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][c:7]1[cH:8][cH:9][c:10]([O:11][CH2:12][CH:13]([CH2:14][NH:18][CH2:19][CH2:20][O:21][c:22]2[c:23]([CH3:35])[cH:24][c:25](-[c:28]3[cH:29][cH:30][c:31](=[O:34])[nH:32][n:33]3)[cH:26][cH:27]2)[OH:15])[cH:16][cH:17]1

Participants

3

Reactant 2

HCID 151078196-[4-(2-aminoethoxy)-3-methyl-phenyl]-3(2H)-pyridazinoneHCID 198846091-[4-(2-Methoxyethoxymethyl)phenoxy]-2,3-epoxypropane

Product 1

HCID 198846446-[4-[2-[3-(4-(2-Methoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-methyl-phenyl]-3-(2H)-pyridazinone

Sources & evidence

ORD record
ord-7454c45000fc42c586c2b92f1c43efeb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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