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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804629Generated: October 25, 2026

tert-Butyl piperazine-1-carboxylate → Tert-butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1804629

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant2-(Bromomethyl)pyridineHCID 564209—
ProductTert-butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylateHCID 10062065—

Reaction Steps

Prepared from 2-(bromomethyl)pyridine and tert-butyl 1-piperazine-carboxylate using the procedure described in Step A of Intermediate 113. LC/MS: m/z (ES) 278.1 (MH)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354403B2
Source datasetuspto-grants-2013_01
ORD IDord-02da9516dbee4b4aa65d6b12ad249001
Source noteuspto-grants-2013_01