HCID 67971713, compound → HCID 67972581, compound

Participants

Reaction Steps

To a nitrogen flushed solution of the title compound from Step D (790 mg, 2.93 mmol) in methanol (10 ml) was added 10% Palladium on carbon (75 mg) and the resulting mixture stirred under a balloon of hydrogen for 2 h. The mixture was filtered through Celite® and the filtrate evaporated to give the title compound 480 mg (91%) as a clear oil. 1H NMR (CDCl3): 1.80 (m, 4H), 2.82 (m, 2H), 2.95 (dd, J 13.1 and 2.7 Hz, 2H), 3.03 (d, J 12.7 Hz, 2H), 4.55 (s, 1H), 8.62 (s, 1H).

Provenance & Evidence