3-Furanmethanol → HCID 66841759, compound

HRID 1804772Notes

Reaction equation

HRID 1804772 reaction equation
[CH:1]1([CH2:5][O:6][C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH:9]=[C:10]([C:16]([OH:18])=[O:17])[NH:11]3)[CH2:4][CH2:3][CH2:2]1.[O:19]1C=CC(CO)=C1.C(OC(C1NC2C(C=1)=C(O)C=CC=2)=O)C>>[O:19]1[CH:4]=[CH:3][CH:2]=[C:1]1[CH2:5][O:6][C:7]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:8]=1[CH:9]=[C:10]([C:16]([OH:18])=[O:17])[NH:11]2

Participants

4

Reactant 3

HCID 204493-FuranmethanolHCID 13274763Ethyl 4-hydroxy-1H-indole-2-carboxylateHCID 591526824-Cyclobutylmethoxy-1H-indole-2-carboxylic acid

Product 1

HCID 66841759HCID 66841759, compound

Procedure

4-(Furan-3-ylmethoxy)-1H-indole-2-carboxylic acid (16c) is synthesized analogous to 16a from furan-3-yl-methanol and 4-hydroxy-1H-indole-2-carboxylic acid ethyl ester.

Sources & evidence

ORD record
ord-c8030c09a33546d983d42945d9ae09c8
Source dataset
uspto-grants-2013_01
Patent number
US08354431B2

Reaction notes

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