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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804777Generated: October 31, 2026

2-Methoxyphenethyl alcohol → 4-[2-(2-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/1804777

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxyphenethyl alcoholHCID 81909—
ReactantEthyl 4-hydroxy-1H-indole-2-carboxylateHCID 13274763—
Reactant4-Cyclobutylmethoxy-1H-indole-2-carboxylic acidHCID 59152682—
Product4-[2-(2-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acidHCID 59152647—

Reaction Steps

4-[2-(2-Methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid (16j) is synthesized analogous to 16a from 2-(2-methoxy-phenyl)-ethanol and 4-hydroxy-1H-indole-2-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354431B2
Source datasetuspto-grants-2013_01
ORD IDord-a3a24b48548e41c2b6fb56b5782e80de
Source noteuspto-grants-2013_01