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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804778Generated: November 1, 2026

3-Methoxyphenethyl alcohol → 4-[2-(3-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/1804778

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxyphenethyl alcoholHCID 78724—
ReactantEthyl 4-hydroxy-1H-indole-2-carboxylateHCID 13274763—
Reactant4-Cyclobutylmethoxy-1H-indole-2-carboxylic acidHCID 59152682—
Product4-[2-(3-methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acidHCID 59152678—

Reaction Steps

4-[2-(3-Methoxy-phenyl)-ethoxy]-1H-indole-2-carboxylic acid (16k) is synthesized analogous to 16a from 2-(3-methoxy-phenyl)-ethanol and 4-hydroxy-1H-indole-2-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354431B2
Source datasetuspto-grants-2013_01
ORD IDord-76ae347a0366439b94c1593a9257e4a9
Source noteuspto-grants-2013_01