HCID 59152645, compound → HCID 25006257, compound

HRID 1804804Notes

Reaction equation

HRID 1804804 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[C:7]([CH2:10][O:11][C:12]3[CH:20]=[CH:19][CH:18]=[C:17]4[C:13]=3[CH:14]=[C:15]([C:21]([OH:23])=O)[NH:16]4)[C:6]=2[CH:24]=1.[NH2:25][CH:26]1[CH2:31][CH2:30][C:29]([CH2:33][CH2:34][N:35]2[CH2:40][CH2:39][C@H:38]([OH:41])[C@@H:37]([CH3:42])[CH2:36]2)([OH:32])[CH2:28][CH2:27]1>>[OH:32][C:29]1([CH2:33][CH2:34][N:35]2[CH2:40][CH2:39][C@H:38]([OH:41])[C@@H:37]([CH3:42])[CH2:36]2)[CH2:30][CH2:31][CH:26]([NH:25][C:21]([C:15]2[NH:16][C:17]3[C:13]([CH:14]=2)=[C:12]([O:11][CH2:10][C:7]2[C:6]4[CH:24]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=4[O:9][CH:8]=2)[CH:20]=[CH:19][CH:18]=3)=[O:23])[CH2:27][CH2:28]1

Participants

3

Reactant 2

HCID 59152645HCID 59152645, compoundHCID 66841564HCID 66841564, compound

Product 1

HCID 25006257HCID 25006257, compound

Procedure

This compound is synthesized analogously to example 1 from 4-(5-chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (synthesis described in WO2005077932A2, cmpd 113) and amine 14.

Sources & evidence

ORD record
ord-0f23c6a635464d87a68ef82e03f44d8c
Source dataset
uspto-grants-2013_01
Patent number
US08354431B2

Reaction notes

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