HCID 59152645, compound → HCID 25005519, compound

HRID 1804810Notes

Reaction equation

HRID 1804810 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:29]=[CH:28][C:10]2[C:11]([CH2:14][O:15][C:16]3[CH:24]=[CH:23][CH:22]=[C:21]4[C:17]=3[CH:18]=[C:19]([C:25]([OH:27])=O)[NH:20]4)=[CH:12][O:13][C:9]=2[CH:8]=1.[NH2:30][CH:31]1[CH2:36][CH2:35][C:34]([CH2:38][CH2:39][N:40]2[CH2:45][CH2:44][C@H:43]([OH:46])[C@@H:42]([CH3:47])[CH2:41]2)([OH:37])[CH2:33][CH2:32]1>>[OH:37][C:34]1([CH2:38][CH2:39][N:40]2[CH2:45][CH2:44][C@H:43]([OH:46])[C@@H:42]([CH3:47])[CH2:41]2)[CH2:35][CH2:36][CH:31]([NH:30][C:25]([C:19]2[NH:20][C:21]3[C:17]([CH:18]=2)=[C:16]([O:15][CH2:14][C:11]2[C:10]4[CH:28]=[CH:29][C:7]([O:6][CH2:5][CH2:4][CH2:3][O:2][CH3:1])=[CH:8][C:9]=4[O:13][CH:12]=2)[CH:24]=[CH:23][CH:22]=3)=[O:27])[CH2:32][CH2:33]1

Participants

3

Reactant 2

HCID 59152645HCID 59152645, compoundHCID 59152661HCID 59152661, compound

Product 1

HCID 25005519HCID 25005519, compound

Procedure

This compound is synthesized analogously to example 1 from 4-[6-(3-methoxy-propoxy)-benzofuran-3-ylmethoxy]-1H-indole-2-carboxylic acid 30f and amine 14.

Sources & evidence

ORD record
ord-2cc270dfc91a41be80c024960539db7a
Source dataset
uspto-grants-2013_01
Patent number
US08354431B2

Reaction notes

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