Diethyl Ether → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(3-trifluoromethyl-phenyl)-acetamide
Reaction equation
[CH2:31]([O:32][CH2:33][CH3:34])[CH3:35].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:13]([C:14](=[O:15])[OH:16])=[O:17])[CH2:11][CH2:12]2)[cH:18][cH:19]1.[F:20][C:21]([c:22]1[cH:23][c:24]([NH2:25])[cH:26][cH:27][cH:28]1)([F:29])[F:30]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:13]([C:14](=[O:16])[NH:25][c:24]3[cH:23][c:22]([C:21]([F:20])([F:29])[F:30])[cH:28][cH:27][cH:26]3)=[O:17])[CH2:11][CH2:12]2)[cH:18][cH:19]1Participants
4
Sources & evidence
- ORD record
- ord-23734fa2063f4ea394c2d1d371d223dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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