HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 67230143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | Methyl 2,3-dihydro-2-oxo-1H-indole-5-carboxylate | HCID 2773516 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67230143 | HCID 67230143 | — |
Reaction Steps
To a solution of methyl-2-oxindole-5-carboxylate (4.764 g) in EtOH (100 mL) was added 4-fluoro-benzaldehyde (4.72 mL) in one portion, followed by piperidine (790 μL). The mixture was refluxed for 3 hours and the yellow precipitate was collected by filtration. The yellow product was used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354443B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-455d81f96b17452ebdb0c153cfc6dd8d |
| Source note | uspto-grants-2013_01 |