HCID 12069904, compound → HCID 69810410, compound

Participants

Reaction Steps

1.03 g (1.25 mmol) of NO2-Bz-TTDA was dissolved into 50 mL of CH3CN, and was mixed with 24.8 mg of Pd/C to form a reaction solution. The reaction solution was charged into a reactor. The reactor was vacuumed for 3 minutes, followed by introducing H2 therein to adjust the pressure to 1.5 kg/cm2, allowing reaction to take place by stirring at room temperature for 4 hours, and evaporating when the pressure in the reactor was kept constant to form a crude product. The crude product was purified using silica column chromatography (eluent: CH2Cl2/CH3OH=19/1) so as to obtain a product of 0.82 g (1.03 mmol, 82.4%) of NH2-Bz-TTDA.

Provenance & Evidence